To demonstrate the capacity of the device for delivering tactile stimulation at four independent sites, a finger agnosia protocol, in the presence and absence of conditioning stimuli, was conducted on seventeen healthy control subjects.
After the validation, we further demonstrated the usefulness of the DCA-L1 method, using actual experimental results taken from a human brain measurement under a finger-tapping protocol.
Throughout all filling and scanning protocols, finger and body TLDs were worn as standard practice.
Although a library of zinc finger components and protocols to perform screens to identify optimized ZFNs has been made freely available to the academic community (Maeder et al., 2008; Maeder et al., 2009), it can take months for non-specialists to engineer ZFNs that target a genomic site with high efficiency.
BP oscillations were measured continuously throughout the protocol from a finger BP cuff attached to the middle finger of the nondominant hand (Portapres, FMS, Finapres Medical Systems BV, Netherlands).
Intra-tester reliability of finger goniometry using a standardised protocol has been shown as acceptable [ 17] with a within-tester error of less than 5 degrees.
For example, the M1 column of Table 1 shows that finger tapping, the simplest motor protocol, had a TtP of 18.13 ± 2.35 s, whereas palm squeezing (14.21 ± 1.84 s) and card flipping (9.55 ± 2.47 s) had earlier TtPs since they used more arm and hand muscles.
In addition to activation by the popular finger tapping and sensory stimulation protocols [ 46– 48], palm squeezing, sequential tapping, and card flipping (supination and pronation) protocols were also demonstrated for this extended FOV.
If consent was given by the patient, whole blood was obtained by finger prick according to standard protocols [ 2].
