Sentence examples for finger cluster from inspiring English sources

In contrast to Ran interaction with RanBP2-exportin-1 complex, exportin-1 binding to the zinc finger cluster domain of RanBP2 is insensitive to leptomycin B and nucleotide-bound state of Ran-GTPase.

The resulting protein differs in the first zinc finger cluster (Figure 6C).

Here we focused on the human 8q24.3 zinc finger cluster comprising seven members near the telomere.

This is not the only kruppel-type zinc finger cluster on chromosome 19 that is associated with tandem repeat DNA, as an extensive cluster at 19p12 is interspersed with blocks of β-satellite [ 44].

It binds to DNA via two zinc finger clusters at its N- and C-termini, and it recognizes target genes through a modified E-box sequence (5'-CACCT(G)).

Finally, we identify a KRAB-ZNF transcription factor that co-localizes with H3K9me3 on C2H2 zinc finger clusters in several different cell types and show that this DNA binding factor is involved in targeting epigenetic regulatory complexes to the human genome.

The Snail family is composed of zinc finger proteins, the ZEB family has two zinc finger clusters and Twist proteins have a helix loop helix motif.

Of the 20 zinc finger proteins targeted by this analysis, most were located on chromosome 19 where zinc finger clusters are known to have undergone recent expansions [ 28].

The zhf family members are characterized by the characteristic flanking zinc finger clusters and homeodomain-like domain in their protein with specific DNA-binding ability [ 17, 18].

Studies revealed that δEF1 is a widely expressed transcriptional repressor, working through its zinc finger clusters binding to consensus E-box-like sequences, 5'-CA(G/C)(G/C)TG-3' [ 33- 35].

The gene is conserved in most bilaterians and usually has a homeodomain flanked by two separate, highly conserved zinc finger clusters.