To characterize the fine specificity of AQP4 p61 80-specific T cells, we examined p61 80-specifico Truncells peptides corresponding to sequences wethin this rexamined
The fine specificity of the AR-specific CTL responses in prostate cancer patients was defined by recognition of two HLA-A2-restricted peptides, AR805 and AR811, with the latter capable of eliciting specific CTLs following immunization of A2/DR1 transgenic mice.
More specifically, enhanced staining may be a consequence of a slightly modified fine specificity increasing the number of structures recognized in the tissue.
This study revealed discrete structural features that determine the fine specificity of 1C1 to EphA2.
Chemokines act as leukocyte chemoattractants with fine specificity for individual leukocyte types.
However, the fine specificity of anti-MSP119 antibodies is also important, as only a fraction of monoclonal antibodies (mAbs) have parasite-inhibitory activity in vitro.
The NASBA-ELISA system was developed by using primers designed by Loeffler J et al. (2001), who proved specificity of the primers and the use of bioth-probe also assured fine specificity for Aspergillus genus.
Using this relationship between the parent monoclonal and the recombinant antibody derived from it as a model, we attempted to identify those residues responsible for this change in fine specificity.
Therefore, to better understand why anthrax vaccination elicits heterogeneous levels of protection, this study was designed to elucidate the relationship between anti-PA fine specificity and LeTx neutralization in response to PA vaccination.
Sera from ΔN2mCHO(Q105N)_MPL immunized animals bound the homologous antigen ΔN2mCHO(Q105N) with greater preference than sera from ΔN2mCHO(QuilA)_Quimmunizedized animals, demonstrating the modulation of antibody fine specificity by these two adjuvants.
A panel of 15-mer peptides (with 11 amino acid overlap) spanning full-length gD2 was used to investigate the fine specificity of T cell responses to gD2 as well as the role of vaccine composition on epitope selection.
