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On the other hand, the divisive method separates the objects successively into finer groupings, eventually keeping each object in a single group.
Key issues such as sample size within the finer groupings and the interpretability of groupings if it is not readily discernable what common underlying factors individuals within a group possess that are influencing their interaction with the task represent major challenges that would need to be addressed.
Therefore, biclusters which are determined from multiple and potentially overlapping gene expression profiles may be more relevant in the context of personalised medicine, which requires finer groupings of patients with specific molecular and clinical characteristics.
For chemicals capable of inducing MN, a classification into aneugens and clastogens suggests itself as a starting point, but additional information will be required to arrive at finer groupings.
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His Time Life The Good Cook series is one of the finest groupings of cookbooks to date.
Initial analyses were undertaken on fine groupings of the maternal and perinatal variables and, following scrutiny, broader groupings - as shown in the tables - were selected for further analysis.
The results employing the described grouping yielded similar results as with the more fine-tuned groupings compiled through LCA (data not shown).
Another strength is that we used a large number of variables to develop the propensity score model, with fine stratification of disease groupings.
Like the human and mouse dendograms, this hierarchical clustering showed functional disease grouping at both a coarse group level and at a fine level within major phenotypic groupings.
The maps show subject groupings and more fine-grained intellectual connections among authors.
It could also be inferred that haplotypic structure would substantially differ at this locus in the two ancestral groupings, aiding in fine-mapping the causal variant.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com