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Idiom
Fine tuning.
Small adjustments to improve something or to get it working are called fine tuning.
Exact(1)
Thus, miRNA as rheostat capable of regulating gene expression for optimal protein output [36] would be a likely component of such fine tuning interaction for the proper functioning of pancreatic islets.
Similar(59)
This allows us to propose that an important role of U1-70k in in fine tuning interactions with either U1-C or Sm-/B/B' in response to incorporation of the different isoforms and their phosphorylation status in vivo.
But the controlled expression of target CCR1 in an uninfected cell inspite of the significantly low expression of its corresponding miR-223 in BASCs suggest that there must be a cascaded fine tuned interaction masterminded by the virus which is going on within the infected cell.
Furthermore, we revealed a so far unreported sparse but reliable inhibitory connection between LVa and supragranular pyramidal cells, which might play a role in fine tuning the interaction of the two signal processing pathways.
From the zP2X receptor structure, the PheThr doublet is adjacent to a conserved lysine residues, and Thr186 may therefore play a role in fine tuning the interaction of the phosphate tail of ATP with Lys70.
Given the highly basic arginine-rich C-terminal sequences of Sm-B/B' and U1-C and the fact that the C-terminus contains all but one of the six phosphorylation sites reported for U1-70k, is is entirely feasible that phosphorylation is responsible for fine tuning the interactions of the negatively charged C-terminal tails with the unstructured regions of positively charged Sm-B/B' and U1-C.
This provides the driving force for fine tuning host-guest interactions at the molecular level and constitutes an entry toward subtle discrimination of different chemicals (e.g. complementary fertilizers, synergistic drugs) during their sequential release.
We conclude that cholesterol can either inhibit or facilitate membrane-Aβ interactions through fine tuning of glycosphingolipid conformation.
The best of the bunch also allow users to fine-tune this interaction, such as by setting the amount of time that location can be tracked.
The parent then practices the activity with the child and is given encouraging feedback to fine-tune her interaction with the child.
It is possible that some of the phase-1 and phase-2 WRKY genes are involved in repression of gene expression to fine-tune the interaction of early (oxidative) and late (ABA) signaling mechanisms.
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