Two authors scored each case independently and discussed discrepancies before providing a final concordance rating (no concordance, minimal concordance, partial concordance, near concordance, complete concordance).
The accuracy of core biopsy for the diagnosis of breast carcinoma is superior to the cytological diagnosis by fine needle aspiration, and a good concordance rate has been reported between core biopsy and surgical biopsy (91 100%), with a specificity rate ranging from 96%to100%0% (Verkooijen et al, 2000).
These data suggest that Mendelian-inheritance error checking is a worthwhile strategy for both types of genotyping data, whereas fine-Mendelian-inheritance errore from checkingnce checkisg than do studies using commercial marker data.
There was no clinical diagnostic impact of this change as the concordance agreement calculations revealed very fine agreement between HER2 CISH and the two FISH assays.
A comparison of immunocytochemical assays for Ki67 and other biologic variables on preoperative fine-needle aspirates with OBE results showed the concordance between cytology and histology was the lowest for Ki67 evaluation: 89% for ER, 78% for PgR, 79% for p53, and 70% for Ki67, respectively [ 28].
We demonstrate a new strategy for fine mapping QTL which combines GWAS data together with daughter design results and concordance testing.
Both nipple aspirate fluid (NAF) and random periareolar fine needle aspiration (RPFNA) evidence of atypia have been shown to increase the concordance statistic based on the Gail model [ 17- 19].
For clinical applications, the prototype assay can be readily fine-tuned by optimizing the conditions for PCR and hybridization to yield concordance levels approaching 100% (data not published).
This observation indicates a general concordance of these two methods, with our method producing a much finer cluster, expressing an explicit pharmacological relationship between responses and treatments.
As a fine-tune evaluation of convergence, we also used the phylogenetic tree comparison tool, which assesses the degree of concordance between trees from replicate runs.
