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The living human brain is not readily accessible to direct investigation, and the dead brain undergoes chemical change; moreover, findings of abnormalities in cerebrospinal fluid, blood, or urine may have no relevance to the question of a presumed biochemical imbalance in the brain.
Certain findings of abnormalities in the T sperm group were further examined under eosin/nigrosin staining or using scanning electron microscopy.
Depending on targeted or non-targeted analysis and on the level of resolution, NIPT for common autosomal aneuploidies may lead to findings of abnormalities in other chromosomes, including submicroscopic abnormalities.
In the absence of anaemia, which is the marker of severe iron deficiency, our findings of abnormalities in several of these indicators (as used in our definition of iron deficiency) implies the presence of a moderate rather than a mild iron deficiency.
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This analysis confirmed the finding of abnormalities present in the right hemisphere, with the location of the clusters the same as the original observation but slightly increased in size, likely because of the reduced number of multiple comparisons.
The finding of abnormalities unrelated to clinical phenotypes illustrates that important pathology phenotypes will be missed if histopathology is restricted to perceived target organs or tissues based on clinical phenotyping.
A number of previous studies have examined the relationship of clinical findings to abnormalities of nerve conduction [ 6, 9- 30], but most have been small [ 10- 15, 15- 18, 20- 24, 24- 28] or have assessed associations with pre-defined composite scores without attempting to disentangle the relative importance of different component symptoms and signs [ 10, 20- 29, 29].
Given that these abdominal abnormalities are critical for patient management, it is important to be familiar with the typical imaging findings of the abnormalities on cross-sectional imaging.
It is hypothesized that the phenomenology of major depressive disorder (MDD) is subserved by disturbances in the structure and function of brain circuits; however, findings of structural abnormalities using MRI have been inconsistent.
Overall, the evidence presented here is consistent with earlier findings of motor abnormalities in BD [3], [5], [6], [7] and is consistent with the proposed deficits in the cerebello-striatal-prefrontal circuit [1], [2].
These protocols also reflect findings of EEG abnormalities commonly found in migraine patients [ 7, 16- 20].
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