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Extrapolations based on both the models are in general quantitative agreement (contained within CIs) with findings from the SEARCH study and the Heart Protection Study.
Not only did the study confirm the findings from the SEARCH study, it also reported an association between the SLCO1B1 risk allele and myalgia symptoms without CK elevation for simvastatin and atorvastatin (weaker), but not for pravastatin treatment [ 16].
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The findings from the searches revealed that the platforms for supporting Internet-based education in most colleges/universities were self-developed, which could be time-consuming, technically challenging and not cost-effective.
The results from the cost analysis were then compared with the financial findings from the literature search previously performed.
The findings from the literature search were discussed by an external expert advisory group (please see acknowledgements).
All the data from the completed proformas and findings from the literature search were combined into a list of potential never events.
The interviewees varied with regard to age, parity and ethnicity, and the information they provided was highly consistent with findings from the literature search.
The main finding from this search was that the only consistently reported findings were delayed recovery and lower remission rates [ 14- 22] as well as faster relapses [ 14, 23- 25] in groups of BD patients with SUD (both lifetime/current substance - and/or alcohol use disorders) compared to BD without SUD.
Finally, mouse often provides a good model for many diseases and the findings from searching the human gene-gene correlations should be supported in the available mouse data.
In addition to the findings from the previous literature search, the categories that emerged from the expert interviews allowed for refining the following research questions (for details see results of the qualitative exploration): 1.
A secondary finding from the literature search was that 55% of cases are undiagnosed – for South Africa this means that about 1 million people with type 2 diabetes do not know they have it.
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