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Furthermore, this finding was validated by loss-of-function analysis showing a more than twofold reduction in luciferase activity in Dsg3 knockdown cells compared with those treated with scrambled control small interfering RNA (Figure 7c).
This finding was validated both in vitro and in vivo, with EZH2 overexpression proving sufficient to drive proliferation in cancer cells and transform primary fibroblasts (Bracken et al., 2003; Croonquist and Van Ness, 2005).
This finding was validated by the GSEA analysis of mRNA expression data (Figure 5B).
However, the finding was validated by demonstrating a decline in excess strong correlations over the random case with fewer samples (Figure S2, where the ratio in number of coefficients, similar to Figure1B, was plotted).
The initial finding was validated in four out of five replication samples, involving a total of 9,881 individuals, with a combined odds ratio (OR) of 1.22 (1.05–1.42) under a recessive model [1].
This finding was validated in the geographically, genetically and demographically distinct Ugandan pediatric population, where ANG-1 (AUC: 0.785, p<0.001) and the ANG-2∶ANG-1 rAUCo (AUC: 0.779, p<0.001) were still the best of the biomarkers examined (Figure 2B, Table 3; sICAM-1, data not shown).
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These findings were validated with qRT-PCR using the validation cohort (N = 32) (Figure 2A and 2B).
Some of the numerical findings were validated experimentally.
The obtained experimental findings are validated against the theoretical results.
The analytical findings are validated by numerical analysis.
These findings were validated through comparison with existing studies.
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