Specifically, the following symptoms and physical exam findings were graded for the above scores as follows: the presence of dyspnea and PND was graded as present (1) or absent (0).
Pathological findings were graded as absent = 0, slight = 1, moderate = 2, high = 3 and severe = 4.
Findings were graded as 0 (absent), 1 (minimal), 2 (moderate) and 3 (extensive).
Fine-needle aspiration cytology (FNAC) findings were graded from C0 to C5 according to traditional cytomorphological methods (Trott, 1985).
The pathological findings were graded as negative = 0, slight = 1, moderate = 2, high = 3, and severe = 4.
The imaging findings were graded on both FFDM and DBT as normal, benign, indeterminate, suspicious or malignant.
Slit lamp examinations were conducted at each visit and the findings were graded on a scale from 0 to 3 (0: normal; 1: mild; 2: moderate; 3: severe).
Funduscopic examination was performed on days 14, 15 and 18 after immunization, and clinical findings were graded from 0 to 4 as previously described [ 31].
The apoptotic findings were graded as negative = 0, slight = 1, moderate = 2, high = 3 and severe = 4 in 10 non-coincident microscopic fields (× 400 magnification).
The findings were graded as mild if the tendon displayed only fusiform thickening, moderate if there were additional hypoechoic areas present, and severe if neovessels were also present on Doppler scanning.
