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The small number of cases may have reduced the likelihood of finding statistical significance.
One drawback consistent in all interventions was the absence of finding statistical significance when HbA1c levels were reduced.
Although variability within the treatment groups prevented finding statistical significance, it is important to underscore that the IL-1b levels in the PCB + LPS and full mixture + LPS treatment conditions were elevated by ~2.5 times that of the vehicle + LPS group.
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These will provide a fair representation of findings, statistical significance, achievement of MID, and the potential effect of unknowns on the decision to be made.
Even though these studies might present the usual strengths of quantitative research (e.g., structured research design, generalization of findings, statistical significance, and objectivity of the researcher), they also have weaknesses.
The age interaction with the predictors was tested without finding any statistical significance or model modifications.
Nashef talks the reader through basic statistics, explaining how a finding of statistical significance is defined, how it depends on size of sample and size of measured difference.
However, despite this demonstrative finding, no statistical significance could be established for this sub-category of "lesions".
Although the finding lacked statistical significance (P = 0.052) there was a trend toward patients who experienced complications to be less likely to reply 'much better' than those who were free of complications [10].
Due to the heterogeneity among very large databases, the data source selected may challenge the results of observational studies, including even finding contradictory statistical significance (Madigan et al. 2013; Goldstein and Winkelmayer 2015; Crump et al. 2013a).
Here, a remarkable difference can be found across the SFSC types and between Trentino and peri-urban contexts, which clearly emerges by looking at the data presented in Figure 3, although this finding lacks statistical significance given the small sample size.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com