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A major finding of this trial concerns the two histological responses of two treated subcutaneous nodules not associated with an apparent clinical response.
The main finding of this trial was that overall outcomes were not significantly different for neonates receiving shorter- versus longer-duration antibiotics.
Major finding of this trial, as in the previous one, was that activity came at no cost of clinically significant toxicity, which is a hallmark of metronomic chemotherapy [ 19].
The novel finding of this trial is that this DNA/PSA vaccine, given together with GM-CSF and IL-2 to patients with prostate cancer, is safe and in doses of 900 μg can induce PSA-specific immunity.
The negative finding of this trial may lead to intensified focus on dietary advice, including carbohydrate counting, stable day-to-day carbohydrate intake, especially in late gestation (36), and weight gain within the Institute of Medicine recommendations (37).
The key finding of this trial was that increased amounts of calories significantly reduced mortality for patients with body mass index (BMI) <25 and BMI ≥ 35, with limited or no benefit of increased calorie intake for patients with BMI from 25 to <35.
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"The implications of the findings of this trial are immediate and global," Dr. Mark Schiffman of the National Cancer Institute wrote in an editorial accompanying the study.
If these two features alone — as opposed to the actual interventions — could explain the findings of this trial, that means we need to figure out how to exploit this effect so that more people can benefit from it.
The sample size was small, therefore the findings of this trial study should not be considered conclusive but rather should be used as a foundation for planning future studies.
Dr Iain Frame, the director of research at Prostate Cancer UK, said: "The findings of this trial are potentially game-changing - we can't wait to see the full results.
Further findings of this trial will be updated.
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