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Our finding of HPV type-specific associations (HPV 31, 58 and 70) raises the possibility that biological processes might underlie the association with HIV risk.
The finding of HPV in 16% of semen samples is comparable with a recent paper on HPV frequency in Danish women [25].
The finding of HPV DNA in actinic keratoses is a reason why imiquimod is effective in treating both external genital and perianal warts as well as actinic keratoses.
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In the case of a reliable cytological squamous cell carcinoma diagnosis, the finding of HPV-positive cancer cells may be sufficient to consider the primary tumor to be an undetectable OSCC and treat the patient accordingly.
Findings of HPV-positive assay results also cause adverse psychosocial impact [ 9].
However, we could not correlate this finding to HPV status due to limited numbers of patients.
Based upon the findings of oral HPV in non-tobacco and non-alcohol associated oral cancers, other recent efforts have focused more specifically to evaluate oral HPV prevalence and transmission within healthy populations, which also confirmed that HPV16 and HPV18 were the most commonly detected oral high-risk HPV strains [ 39- 41] among healthy adults.
Here, we report the histological findings and results of HPV typing performed on skin biopsies taken from affected sites in 4 HIV-infected adolescents in Harare.
Our finding of >70% HPV prevalence in a large sample of the oropharyngeal cancer patients from around the United States suggests that a substantially higher faction may be HPV-related than has been reported in many previous investigations (14 ).
A consistent finding from our cohorts of HPV positive and negative pregnant women and their offspring is the evidence for horizontal transmission.
In some studies with conflicting findings, the prognostic value of HPV was determined for all HNSCC anatomic sites (9 ).
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