Earlier work in this area mainly focused on finding linkage-based communities on small networks.
Due to the expected locus heterogeneity for causative variants leading to keloids [ 32- 34], recruitment from the Yoruba population seemed ideal for finding significant linkage because of relatively low admixture [ 35, 36] compared to many other populations.
This finding provides broader support for the link between marketing capabilities and innovation among SMEs (Banterle et al. 2011) by finding a similar linkage with respect to a market orientation to product and marketing innovation within another context.
Within this convergence of peaks there was also a suggestive linkage finding for theta EEG power (LOD = 2.2).
No significant difference was detected in the genotype or allele distribution between cases and controls, suggesting that our linkage finding in South Indians does not extend to genetic association in an American population of mixed European ancestry.
Further sequencing and analysis of the region will be required to elucidate the basis of this linkage finding.
18 Orenstein and colleagues, however, failed to replicate this linkage finding in a different GORD family material.
For this complex trait, modeling the covariance matrix with covariates, mainly environmental factors were explained, resulting in an increase of the heritability and subsequently the chance of finding genes by linkage and association studies.
In a similar vein, the long-run co-movements between markets are studied by Chung and Lin (1994) in Japan, the U.S., Taiwan, HongKong, and Singapore over the period 1985 92, finding weak financial linkages.
Family-based linkage analyses have also been conducted in two studies, finding significant evidence for linkage at 12q12.22 (Vasa-Nicotera et al. 2005; Mangino et al. 2008) and 14q23.2 (Andrew et al. 2006), although neither study appears to replicate the other's findings.
We replicated the finding of linkage of the chromosome 5q31 region to P. falciparum asymptomatic parasite density that has been previously reported in three independent studies [12] [14].
