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The screen revealed ubiquitin ligases that, when knocked down, reduced the extent of phospho-H2AX accumulation [ 3].
The decrease of p-AKT was also observed when knocking down LIS1 by siRNA.
We observed that none of the genes, when knocked down, significantly affected primary tumor growth.
An interesting finding is that the gut development of Tribolium embryos is affected by MMP-2 knock-down.
Here the turquoise module is made of genes that are activated when Oct4 is knocked down, while the black module contains genes that are repressed when Oct4 is knocked down and are down-regulated during retinoic acid (RA) induced differentiation.
When Brewer is knocking down that shot, it makes it that much easier for everyone else".
These findings suggest that the production of BSE-resistant cattle would be possible by knocking down bovine PRNP (b PRNP) using RNA interference (RNAi) technology.
TGF-β1 stimulates PDL cell proliferation, however, this effect is compromised when LMP1 is knocked down.
CSN6/COP1-mediated 14-3-3σ ubiquitination is compromised when COP1 is knocked down.
In accordance with our previous finding in SH-SY5Y cells and patient fibroblasts, the mitochondria in HeLa cells were fragmented when mortalin is knocked down.
P Plant growth cannot be sustained under boron-deficient conditions when expression of that gene is knocked down using RNAi.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com