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Figure 12 illustrates vascular imaging findings of interrupted IVC with azygos continuation.
Our findings with interrupted and uninterrupted arrays of tetranucleotide repeats therefore disagree with those of prior studies that found uninterrupted arrays of di- and tri-nucleotide repeats to be more polymorphic than those with interruptions both in genomic DNA [ 47, 86, 88] and plasmid construct [ 87, 89] environments.
The finding that patients who had thrombolysis interrupted because of bleeding received less rtPA was expected.
We used an interrupted time series design to evaluate the effects of incentivised case finding while accounting for underlying secular trends.
However, the recognised possible threats to the validity of findings from any interrupted time-series analysis need to be considered, including 'history' (ie, events that coincided with the intervention may have caused the observed change) and 'instrumentation' (ie, that the data collection method changed when the intervention was launched).
This article complements papers reporting how the programme was developed (Atkins, S, Lewin, S, Ringsberg, KC, Thorson, A: Developing a new model of tuberculosis treatment support in Cape Town, South Africa: A qualitative process analysis, submitted); the findings of a parallel interrupted time series study of the effects of the programme [ 15]; and a study describing patient experiences [ 16].
The usefulness of the black surface color as a predictor of caries activity was shown by the finding that lesions with an interrupted or lost black surface were 4.6 times more likely to have decay progression.
Pattern of disease burden in this study reaffirms Hill et al [ 32] findings of epidemiological transition but interrupted by the 1990s HIV/AIDS epidemic.
This finding and a recent analysis of an interrupted Alzheimer's vaccine trial in people have brought new life to the idea of immunotherapy for the debilitating disease.
A more recent study using interrupted time series analysis has confirmed these findings and the authors believed that the effects were due to changes in the quality and quantity of reporting [ 23].
Moreover, the finding that ATXN2-linked parkinsonism may be associated with an interrupted CAG repeat region, versus the pure CAG repeats typical of SCA2, raises the possibility that the CAG purity of the repeat expansion may contribute to disease manifestation.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com