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This assumption is supported by a report finding disruption of rRNA processing in human cancer cells after expression of exogenous sense and antisense nc-rRNAs from the 5′ETS region.
The core finding, disruption and change, illustrates the range of perceived consequences of knee symptoms in peoples' lives.
(Davis, age 61, focus group 5) The core finding, disruption and change, illustrated the consequences of knee symptoms on peoples' lives (figure 1).
40 Consistent with this finding, disruption of the HA CD44 interaction in vivo by systemic administration of an anti-CD44 monoclonal results in a rapid permeability increase.
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He points to similar studies of collegiate athletes finding disruptions in brain connectivity immediately following a concussion, like one published in 2011, in which researchers at Pennsylvania State University scanned the brains of seventeen rugby, ice hockey, and soccer players about ten days after they suffered concussions.
Our finding that disruption of the spermidine transporter exclusively down-regulated the T3SS genes seems to suggest a rather specific mechanism by which the polyamine signals act on.
This hypothesis was supported by our finding that disruption of mutS, mutL, or mutS2 did not cause a drastic decrease in the survival ratio under H2O2 (below 30 mM -induced stress but in a significant increase in the rate of 10 mM -induceduced mutagenestressig. 5A–C).
Our finding that disruption of the actin cytoskeleton results in a compromised Ca2+ wave hints at signalling through an actin-IP3 receptor interaction.
This is confirmed by the finding that disruption in microglial function, such as depletion of microglia CX3CL1 receptor or administration of a microglial inhibitor, results in delayed synaptic pruning and maturation of hippocampal synaptic circuits (Paolicelli et al., 2011, Schafer et al., 2012).
In line with our findings, disruption of Sfrp1, a Wnt antagonist, resulted in a female-preferential bone phenotype [29].
Consistent with these findings, disruption of the hairpin structure in the Met-Ala variant abolishes the recognition of GCG and protein synthesis in this variant starts at the first AUG present in the sg-mRNA.
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