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Striatal dopamine transporter (DAT) imaging is a sensitive biomarker of substantia nigra pars compacta (SNc) neuronal density that may improve the accuracy of in vivo diagnosis in patients with CBS, given that SNc cell loss is a pathological finding considered to be mandatory for the definite diagnosis of CBD [3], [16], [17].
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The observers classified each std-SPECT/CT and UF-SPECT/CT result separately into one of three categories: (1) normal findings or findings considered to represent benign conditions (M0), (2) equivocal findings in which changes were observed on std-SPECT/CT or UF-SPECT/CT but could not be categorized as benign or malignant (Me), or (3) findings of bone metastases (M1).
Employing a previously published classification by Hellstrom et al., findings considered to be of no or little clinical importance were classified as minor and unlikely to require further diagnostic procedures or medical therapy [29].
There were no macroscopic findings considered to be related to the treatment of the green mussel formulation.
Those findings considered to be of clinical and scientific interest are then re-tested on the validation set.
An extracolonic lesion of C-RADS E3 (likely unimportant finding, incompletely characterized) or E4 (potentially important finding) is considered to be clinically relevant.
When neither finding type nor location was available from truth, any marked finding was considered to match the real lesion.
This finding is considered to be evidence for excitation of several TE modes.
This finding was considered to be valuable in PCR-based analysis for detecting T-cell clonality in canine lymphoma/leukemia.
This finding is considered to be a dental compensation commonly found in the side of chin deviation and should be corrected by means of orthodontic treatment.
This finding is considered to be a significant achievement in tumor therapy and it forms a basis for further studies in animal models.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com