This finding classifies CDT, iota toxin and CST into the subfamily of iota-like binary toxins.
In this manner, Römer et al. were able to identify 90% of SPECT findings classified as indeterminate [11].
Nine patients in the IBD group presented with 10 extraintestinal findings classified as tumor, metastasis or mass.
In 12 patients with SBD and 33 patients with SBM 7 of 13 (53.8%) and 11 of 49 (22.4%) of the findings classified as tumor, metastasis or mass were newly detected.
See table 5 for the detected extracolonic findings classified according to the C-RADS classification and the additional procedures that have been performed.
Only one study reported that all findings classified as benign were followed up in the interval between two screenings (Kolb et al., 2002 [ 48]).
One hundred and seventy-five consecutive patients with solid breast masses on routine ultrasonography undergoing percutaneous biopsy had the greyscale findings classified according to the American College of Radiology BI-RADS.
In univariate analyses, a VEGF decrease, radiologic findings classified as progressive disease, and major vascular invasion were associated significantly with 1-year survival; and, in multivariate analysis, a VEGF decrease was identified as an independent factor associated significantly with survival.
However, in the aforementioned study only the medial meniscus was evaluated, whereas the findings classified as subclinical lesions in our study were seen on the lateral meniscus, which is relatively easy to observe during lateral arthrotomy.
An experienced thoracic radiologist (JV), blinded to the patient's clinical history and to the PET findings, classified the scans of both lungs using a semi-quantitative HRCT scoring system that has been described by Oberstein et al. [ 27] and that has been used in previous studies by our group (a detailed description of this scoring system is shown in the Appendix) [ 28].
