Viewers and listeners tuning in to BBC News programmes on Friday morning found disruption to the breakfast shows on BBC1 and Radio 5 Live and Radio 4's Today owing to a 24-hour strike by journalists.
In parallel, we found disruption of RPE contacts with photoreceptor outer segments, which resulted in widening of the inter-photoreceptor matrix space (Fig. 4E, F).
In pig, Wagner et al. found no disruption from 1 to 8 hours, but found disruption by 24 hours [ 10, 11].
Carolyn [ 28] found disruption of terminal myeloid differentiation and cell cycle regulation to be prominent in Evi-1-induced leukemogenesis.
Pavin et al. [ 9] localised laminin around the islets of NOD mice and found disruption of the peri-islet basement membrane associated with intense infiltration by inflammatory cells.
Moreover, among the other dysregulated pathways identified by DINA, we found disruption of fundamental pathways regulating liver cancer progression such as the PPAR signaling pathway (Supplementary Table S19).
In later stage embryos, we found disruption of pronephric development (Fig. 2H,H*) and myotomal organization (Fig. 2I N) on the morphant sides of embryos.
In addition, we found disruption of the A588 elastase cleavage site, through the introduction of an Ala-to-Gly mutation, protected PGRNA588G from elastase processing, hence preserving the SORT1-interaction motif and PGRNA588G endocytosis (Fig. 3C).
Molecularly, we found disruptions in Hedgehog signaling.
We found that residents were often suspicious of strangers and found disruptions to their expected daily routine a little unsettling.
