Sentence examples for finally increased expression of from inspiring English sources

Finally, increased expression of HIF-1α and HIF-2α was found to be correlated with VEGF expression.

Finally, increased expression of GD1b and GT1b in rat pheochromocytoma cells transfected with GD3 synthase occurs in parallel with trk-A dimerisation (Fukumoto et al, 2000), which in turn is associated with improved prognosis in NB (Nakagawara et al, 1993).

Finally increased expression of COX2, a gene with cell cycle modulatory effects as well as antiapoptotic, proangiogenic, and proliferative effects via prostaglandin E2 [ 30, 31], has also been repeatedly associated with poor survival outcomes [ 32].

Finally, increased expression of HIF-1 α and the downstream target GLUT-1 have been associated clinically with tumour metastasis and poor prognosis (Younes et al, 1997; Haber et al, 1998; Zhong et al, 1999).

These results indicated estrogen mediated induction of ERα leads to up-regulation of ETS-1 transcriptional activity, and finally increases expression of ETS-1 downstream genes, such as MMP1/9 in an ETS-1 dependent manner.

57 Finally, smokers have increased expression of 5 genes involved in tight junction function (OCLN, CTNNA1, CLDN7, CLDN10, and TJP2).

Finally, we detected increased expression of a glucoamylase gene (GH15) and an α-galactosidase gene (GH27) in the bottom section (Table  1), which are known to be involved in the mobilization of starch and the degradation of galactomannans (with endo-1,4-β-mannanase) and other galactosides, respectively.

Finally, we detected greatly increased expression of GRP78 (78 kDa glucose-regulated protein), a typical marker of ERS (ER stress) and found that the formation of autophagosomes was closely related to the expanded ER membrane.

Finally, the investigators found increased expression of a chemokine called monocyte chemoattractant protein-1, or MCP-1 (also known as CCL2), which has been implicated in tumor development and angiogenesis, in tumor tissues from the ethanol group and in E0771 cells exposed to 0.2percentt ethanol.

Finally, there appeared to be increased expression of β-dystroglycan in the treated dystrophic mice, which appeared to have normalized toward wild-type levels.

Finally, Flachs et al [179] showed increased expression of genes for mitochondrial proteins in adipose tissue.