The fourth year will be required to finalise data collection and analysis.
Following recruitment of the final woman, it will take 46 weeks to finalise data collection.
An additional 12 months will then be required to finalise data collection and six months to complete data analysis and prepare manuscripts for submission to peer reviewed scientific journals.
"The odds of there being any left is incredibly low," Mountford says, explaining that the blood will go through two terminal filtration processes to remove any undifferentiated stem cells, "and we're just finalising the data on whether there is any persistence of these cells".
A detailed statistical analysis plan will be produced and finalised prior to data lock and transfer to trial statistician.
All economic analyses were carried out on an intention-to-treat basis using an analysis plan finalised prior to data analysis.
R.A.A.: study design, data collection, analysis, drafting and finalising manuscript; M.R.: data collection, drafting and finalising manuscript; T.W.K.: data analysis, drafting and finalising manuscript; D.A.C.: study design, data analysis, drafting and finalising manuscript.
Two reminders were sent in September and the data was finalised in October 2008.
ML planned and coordinated the study, designed the real-time PCR assays, analysed the data and finalised the manuscript.
Other staff verify the notification, validate the information already held and abstract additional information from hospital medical records and local hospital systems before the data are finalised.
