Final diagnoses of lower respiratory tract infection were divided into pneumonic lower respiratory tract infection (LRTI), non-pneumonic LRTI, and non-LRTI.
The alveoli are the final branching of the respiratory tree, where the gas/blood exchange occurs.
Cytochrome c oxidase is the final enzyme of the respiratory chain.
ATP synthase, the final enzyme in the respiratory chain, resides in the mitochondrial inner membrane and generates most of the ATP in aerobic tissues.
Another child grew Haemophilus influenzae from an endotracheal aspirate and had a final diagnosis of lower respiratory tract infection.
His blood culture was negative for any organism, and his final diagnosis was upper respiratory tract infection.
We also measured the activities of citrate synthase (CS, the first enzyme in the tricarboxylic acid cycle, used as a marker of the mitochondrial mass), lactate dehydrogenase (LDH, which catalyzes the conversion of pyruvate to lactate in the cytoplasm) and cytochrome oxidase (COX, also known as complex IV – the final acceptor in the respiratory chain).
Moreover, the correlation between the APACHE II score and the two biomarkers MR-proADM and PCT was tested in the following groups of patients, divided according to the final ED's diagnosis: respiratory infections group, urinary infections group, sepsis and septic shock group, unspecified fever group, and "other" group (Table 2).
As for the final step of the respiratory chain, L. hongkongensis genome encodes three terminal cytochrome oxidases, namely type aa 3 oxidase (a haem-copper oxidase), type cbb 3 oxidase (another haem-copper oxidase) and type bd oxidase (a quinol oxidase).
