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The final method is a reformulation that introduces a new integer variable representing the total number of batches of a task.
GAIA data are also used in environmental risk assessments with product-specific exposure data as a final check during product reformulation or as a post hoc measure of progress toward corporate sustainability goals.
The radiochemical synthesis of 4-[18F]FEBZA (4) waccomplishedhed through a simple one-step fluoro-for-tosyl exchange reaction and is shown in Fig. 2. The total time required for the synthesis, HPLC purification, and reformulation of the final product in buffer required less than 1 h.
Finally, views on product reformulation were mixed.
Clifford Jones, the project manager for the Army Corps reformulation study, said that a final draft would be completed by 2005.
Deprotection of the amino acid moiety was achieved by hydrolysis and the final radiotracer was purified by semi-preparative HPLC and obtained, after reformulation, as a physiological and injectable solution.
Reformulation into ethanolic saline or sterile water resulted in final doses with acceptable pH values (pH = 5.5) for evaluation in animal studies.
The 18F-peptide was obtained, after HPLC purification and reformulation, in 124 132 min from the end of bombardment with a final decay-corrected yield of 7% ± 1.
"Now they will delay the reformulation project.
"A cylindrical reformulation of Heegaard Floer homology".
"That reformulation was key," Stark said.
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