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All participants will be followed for at least 1-year; however, we will continue to follow all participants until the final randomized individual has reached the 1-year mark.
Primary endpoint analysis of the final randomized patient is expected in April 2013.
The final randomized genome is constructed by reassembling the randomized genes and intergenic segments in their original order.
The outcomes will be assessed during the study until the final randomized patient has completed a minimum of 6 months of follow-up.
The efficacy of triple- versus each dual-combination treatment in reducing SeBP within age subgroups was assessed using two-sided p-values derived from an analysis of covariance (ANCOVA) model that had baseline BP as a covariate and final randomized treatment, subgroup, and final randomized treatment by subgroup interaction as fixed effects.
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The study has recruited 9795 patients; the final patient was randomized on 3 November 2000.
The final patient was randomized to the study on 3 November 2000.
Hard copies of all de-identified final panoramic radiographs were randomized and evaluated separately by three orthodontists (CC, CP, and DC), each of whom had at least 20 years of clinical experience.
The final analyses included 274 randomized patients.
Day 3 stimulated salivary flow rates were used to confirm significant reductions due to radiation exposure (figure 1B) and then all animals were randomized into final treatment groups.
The final 133 subjects were randomized into the NV+AB (n = 45), NV-only (n = 44), and control (n = 44) groups.
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