Your English writing platform
Discover LudwigExact(12)
Transporting the protein across membranes may require one pre-folded conformation; final folding then occurs after the protein is in the target organelle (e.g. the endoplasmic reticulum) [36].
To evaluate this "human computing" strategy, Baker recently challenged FoldIt players to perform the final folding of 10 proteins.
This is followed by a final folding of the CDR3 loops of the TCR over the peptide [28].
Final folding of HPLC-purified peptides was facilitated by air-oxidation for at least 48 h at 25°C in TFE and 10 mM ammonium bicarbonate buffer (4∶6, v∶v) at pH 8.0 [55].
Transient binding of all these components might protect the head-platform interface in a chaperone-like way from non-productive interactions with abundant cytosolic (translation related) factors, thereby opening a time window for final folding, and eventually assembly events, which could be further actively promoted by Prp43p's RNA helicase activity.
These optical models were formulated to calculate TIR tolerances of the lens, as well determine as the location and angle of the final folding mirror.
Similar(48)
Additionally, the funnel-shaped landscape predicts the experimentally observed robustness of the folding process to destabilising mutations: if the final fold remains the most stable state relative to the unfolded ensemble, a mutation may block some of the pathways to the native state but alternative folding pathways can be utilised [17].
After the final fold, place the ball of dough on a sheet of parchment.
Final fold change values were estimated relative to the UBC6 gene in the control strain replicates.
Remove bowl from mixer, give a final fold with a spatula and pour into prepared cake pan.
All three of the designs were so intricate that it would have taken him hours just to crease the paper in preparation for the final folds.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com