Regional anticoagulation with citrate in continuous venovenous hemodialysis (CVVHD) reduces the frequency of bleeding complications, provides longer filter lifetime [ 1- 3], and may reduce mortality in ICU patients [ 4].
The three-dimensional structure of a fibrous filter determines its behaviour during filtration, such as the obtained pressure drop, the fractional efficiency and the filter lifetime.
Endpoint for efficacy was the filter lifetime.
Additionally, we analyzed the filter lifetime.
Mean filter lifetime was 78 ± 2 hours.
The endpoint for efficacy was filter lifetime.
We focused on the filter lifetime, delivered dialysis dose, and control of acid-base balance.
The observed median filter lifetime of the first filter without censoring for non-clotting events was 70.4 h.
The mean filter lifetime before diagnosis of hep-PF4 ab was 8 (range 1.3 to 14) hours.
The protocol was safe and easy to handle and the mean filter lifetime was 61.5 hours [ 1].
The filter lifetime censored for non-clotting treatment interruptions even improved compared with the first results published some years ago [ 6], using the same protocol for RCA-CVVHD.
