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iRefWeb allows filtering interactions by specifying a threshold (say, three or more) for the 'Number of Interacting Proteins' in the consolidated interaction record.
Filtering interactions provided 644 interactions between 8 Hproteinsteins and 405 human proteins.
As a result of filtering interactions and modules by confidence levels, the heterogeneity of modularity maps that depends on both methods and interactome datasets may be reduced according to a better control of the uncertainty levels.
'Filtered' entries were defined as interactions having no primary reference for either one of its interactors (even if the interactor has a human readable name) and complexes referencing any 'Filtered' interaction.
— pourmecoffee (@pourmecoffee) 12 Sep 13 Today Twitter lets us filter interactions to only see Verified users.
InnateDB also has a function to filter interactions simultaneously in the graph and the table.
However, interactions identified based on homology alone need rigorous evaluation in order to filter interactions in biological context.
The program can filter interactions based on user defined parameters of minimum number of references per interaction or by maximum number of interactions per reference.
DroID also contains searchable gene information from Flybase, the central repository for Drosophila gene information [ 26], enabling users to find or filter interactions based on Drosophila-specific gene attributes.
In a future release of CTD, users may have the option to filter interactions based upon their HTP status, in case some users prefer to exclude high-throughput data from their analysis.
Since this kind of network contains a lot of noise and does not relate to specific tissue, we re-filtered interactions using a co-expression model based on microarray data.
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