Exact(2)
The atomic notch filter poses an alternative to commercial available filters.
These strings can be clustered and compared using Tanimoto similarities, and used to rapidly filter poses for the presence or absence of specific interactions, providing an improvement in virtual screening hit list enrichment over conventional scoring functions.
Similar(58)
Consequently, spam filtering poses a special problem in text categorization, of which the defining characteristic is that filters face an active adversary, which constantly attempts to evade filtering.
And software filters pose the same risk of inadvertently blocking desirable e-mail messages, especially since spammers have found ways to make their messages look ordinary.
Although high-resolution perfusion CMR offers further intriguing opportunities for quantitative analysis the algorithms applied for the reconstruction of high-resolution perfusion CMR data acquired with temporospatial undersampling methods give rise to a degree of low-pass temporal filtering, posing additional challenges to quantitation of MBF including an underestimation bias.
Rather than applying pharmacophores to filter docked poses directly, the AutoShim method [45] uses point pharmacophore interaction features in the binding site to weight or "shim" the docking scoring function according to experimental IC50 data for the target receptor, and can produce large improvements in the ability of the scoring function to predict binding affinities.
The experimental results demonstrate the feasibility, effectiveness and robustness of the proposed adaptive extended Kalman filter enabled pose and motion estimation and visual servo strategy.
Royte, who wrote a book about garbage and is one of the most eloquent voices on the problem of waste, visited the Orange County plant that is the best, most technologically advanced example of this process, and in addition to entertainingly describing the work of microfiltration bays and osmosis filters, she posed some interesting questions about our hard-wired disgust instincts.
We further apply some concepts of outlier rejection for deriving a robust Kalman filter-based pose estimator.
Many existing privacy preserving collaborative filtering schemes pose challenges with practical implementations on real world cloud computing platforms.
The pharmacophores are elucidated based on available crystal structures of bound ligands and/or simple examination of the binding site, and are used to filter the saved poses output from the docking program, and remove any that are incompatible with the model.
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