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This could be explained by the small sample size filing to detect a true difference if it indeed existed.
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However we have filed to detect a difference in the rate of evolution with the method used here.
We previously provided a script that searches input files to detect and avoid those possible misidentifications [ 20].
For the analysis of NGS data, it processes Bam or Pileup files to detect ROIs using the read-depth at base pair position.
As raw traces are increasingly being deposited in these repositories, there is a genuine need to reprocess trace files to detect both previously ignored and newly recognized sequence features with potential biological meaning.
The main purpose of the bootstrap file is to detect the browser type, select the matching HTML file and load it.
A more extensive list of independently validated CNV regions, and the raw hybridization or other data files used to detect them, should be made publicly available.
Alignment results were produced in BAM file format to detect variations by variant caller algorithm.
The power calculation was performed (Table S2 in Additional file 1) to detect false-positive and false-negative association results.
Since it was not possible to bridge the deletion in MM106, we used PCR primers specific for the SACPD-C locus (Additional file 3) to detect homozygous mutants.
In this work, we performed whole-genome sequencing on 15 hormone receptor negative breast cancers (Additional file 1) to detect somatic gene rearrangements.
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