Considering the randomized request probability of the i-th file p i, when there are n users generating requests, the sum of the effective data rate can be written as: {mathcal{R}}left({n,x} right) = sumlimits_{j = 1}^{n} sumlimits_{i = 1}^{M} {p_{i}}{R_{ij}} (4).
Microscopic examination of tumor cross sections showed significant reduction in the number of intratumor blood vessels in treated (4.6 ± 0.5/microscopic field) compared to untreated animals (7.8 ± 1.2/microscopic filed), P = 0.001.
We observe that combining methylation and copy number information leads to significantly better results in predicting gene expression than taking each information separately (Fig. 9 a, Additional files 16– 17a, P Breast < 10−16, P Lung < 10−9, P Colon < 10−8).
Panagen shows hepatoprotective activity counteracting the activities of chemotherapeutic drugs cyclophosphamide, doxorubicin and fluorouracil (Additional file 2, p. 32 38; Additional file 3, p. 38 50; Additional file 4, p. 16 24).
Additional file 4: An Excel file containing p values associated with the fitness during survival in DC, arranged by functional group.
In both FAC and AC chemotherapies, we observed progressively fewer neutropenias in Panagen patients facing the increasingly negative effects of chemotherapies, as compared to the placebo cohort, where the frequency of neutropenias increased (Additional file 2, p. 13 15; Additional file 3, p. 15 16).
The results are shown in Supplementary Tables S4 [see Additional file 9] and S5 [see Additional file 10] (P value ≤ 0.05).
We repeated the analyses described above using mRNA data, and we identified 66 genes significantly associated with recurrence, and 38 associated with OS (Table S2 in Additional file 6 and Table S3 in Additional file 7; P < 0.05).
Additional file 7: P -values of differences in gene expression between groups on day 0. NS: not significant with P > 0.1.
