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The Cohen Kappa macro syntax file was computed using SPSS12 software to calculate the multiple inter-rater agreement (>2 raters).
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This is because the current version of "pdb_pfam_mapping.txt" file is computed using HMMER3 which operates only in local alignment mode, and hence, the Pfam domain might not fully cover the whole SCOP-PDB entry.
The resulting output files were computed for the detection of overlapping TR, and the canonical motif was defined using in-home Perl scripts.
Posterior probabilities of concatenated files were computed using Bayesian inference [ 32] (Jones model with gamma estimated from data; 10,000 generations; 4 chains with temp = 0.2).
The module network (Additional file 4) was computed using four Cdc25 and four Elu data (Oliva Elu 1&2 not used) with Genomica [ 64].
The resulting sequences were aligned with the Fur homologues from the Actinobacteria [see Additional File 4] and a NJ tree was computed [see Additional File 5].
Before the manual annotation of the predicted genes (Additional file 1), automatic annotation was computed using different tool results as follows: similarity searches were performed against different databases including KEGG, Swiss-Prot, TrEMBL, and NR using BLASTall v.2.2.21 software.
magadii was computed (Additional file 2: Table S2), Nmn.
The calibration curve for the MI threshold was computed (Additional file 3: Figure S10B) and used during network reconstruction.
For example, in one experiment by Levy et al. [ 15], 0.1% of the population was sorted out using flow cytometry and the growth rate distribution of that fraction was computed (Additional file 1: Figure S1I).
The distribution of intensities for XIST in male and females was computed (Additional file 3: Figure S9), and the background threshold estimated as the median value of the distribution in males (log2 median intensity = 5.32).
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