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On the basis of a set of validity criterion we find that Bayesian bootstrap predictive mean matching and the EM‐bootstrap methods perform best with respect to creating a usable synthetic data file for research purposes.
The LHID 2000 is a standardized sample file for research use provided by the National Health Research Institute, and consists of comprehensive use and enrollment information for a randomly selected sample of 1 million NHI beneficiaries, representing approximately 5% of all enrollees in Taiwan in 2000.
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To date there are no documented set of standards for best practice integration of heterogeneous data files for research purposes.
The Netherlands Brain Bank (NBB) performs rapid autopsies of donors who gave written informed consent during life for the use of their brain tissue and medical files for research.
In exchange for this benefit, Ono's 1.4 million users can choose to release information on their file-sharing behavior, such as the timing of downloads and the size of the shared files, for research purposes.
The data used in this article have been downloaded from the OECD website in October 2014 in the form of anonymised public use micro-data files for research purposes (http://stats.oecd.org/Index.aspx?datasetcode=talis_2013%20).
The National Health Research Institutes transferred national health insurance reimbursement data into files for research.
Other information was taken from 'administrative files' for research purposes without approval from an ethical review board.
Availability of the process modes: The models are available in supplementary files for research and non-commercial uses (Additional files 2- 5).
The original quality-assured data file released for research in 2008 (version 4) consisted of data on 72,934 women.
Note that the sample sizes at the different time points may deviate somewhat from previous AHUS publications due to small changes in the latest quality-assured data file released for research.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com