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Utilizing a coarse-grained model, a filament network is prescribed within a two-dimensional circular space through nodal connections.
The model investigates the effect of the surrounding filament network and the cytosol on the microtubule buckling.
Central to understanding cellular response to mechanical stimulation is the organization of the cytoskeleton and its actin filament network.
Therefore, the actin filament network does not push directly toward the surface but rather accumulates, building up stress around the Listeria surface.
It finds that relatively weaker crosslinks lead to a more flaw tolerant intermediate filament network that is also 23% stronger than the one with strong crosslinks.
Defects in K5 K14 filament network architecture cause basal keratinocytes to become fragile, and account for their rupture upon exposure to mechanical trauma.
This scan gave them the 3D topology of the filament network.
Glutathione has been reported to restore the actin filament network in FRDA cells [21].
A snapshot of the lamin intermediate filament network is shown in Figure 1B.
As shown in Figure 8 the procedure well preserved the 3D organization of the filament network.
What happens to the morphology of the intermediate filament network as cells are deformed?
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