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Figures were obtained using Mathematica.

However, these figures were obtained using different sequencing coverage, sampling different anatomical sites and analyzing samples pooled from different number of individuals.

Images shown in figures were obtained using a Zeiss 63 × Plan-Apocromat oil immersion lens, whereas images acquired for F-actin quantification were obtained using a Zeiss 40 × Plan-Apocromat oil immersion lens.

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The curves in both figures are obtained using the actual, not the estimated, equilibrium allele frequencies.

The calculation and the figure were obtained using the freely available R software (version 2.15.3).

Fluorescent signals in Figure  2Q' , Figure  4C and Figure  4C' were obtained using the fluorescent signal emitted from NBT/BCIP precipitate, an alternate method to reflection microscopy.

The left figure was obtained using the conventional estimator (see (10)) and the right figure was obtained using the geometrical estimator (Figure 4).

The result in the upper part of the figure was obtained using direct UV detection at 254 nm, whereas that at the lower part was obtained using visible detection at 412 nm after post-column reaction.

Also, please indicate if the data presented in Figure 4 and Figure 5 were obtained using inside-out patches. 5.

Figures 5 j 5 ll) were obtained using secondary masks given in the order of the experiment number (1 corresponds to (j); 2 to (k), and 3 to (l)).

The images of MIF presented in Figure 1 were obtained using atomic force microscope Veeco Dimension 3100 (AFM; Veeco Instruments Inc., Plainview, NY, USA). Figure 1 AFM images of silver nanoislands on the surface of the glass annealed in hydrogen.

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