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All statistics and figures were computed with the statistical software SPSS SPSS Inc.., Release 10.0.7, Chicago, IL, USA).
The lifetime cost figures were computed with adjustment for survival, using the survival rates for the Danish population in 2007, and truncated at age 90.
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This figure is computed with data extracted on 15 May 2016 from http://www.pension-watch.net/ and the United Nations World Populationn Prospects 2015 revision.
Two sets of modules were computed with 10 000 network permutations and are shown in Supplementary Figures S2 S3.
Protein alignments were computed with ClustalW [31].
Bootstrap values were computed with 1000 replicas.
Bootstrap values were computed with 100 replicates.
The multiple alignments reported in the [Additional file 2: Supplemental Figure S2] and in the [Additional file 3: Supplemental Figure S3] were computed with ClustalX and visually inspected afterwards.
Likelihoods were computed with PAUP.
All models were computed with STATA SE 10.0.
Statistics were computed with GraphPad Prism Software (San Diego, CA, USA).
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