14) Figure 2C/E: Should be shown on a semi-log plot.
If yes, then a clearer image with highlights for the different markers as nicely done in Figure 1a-f should be shown.
2) The quantitative data for NPC cap formation in a bud6∆ mutant should be shown in Figure 2. 3) In Figure 11C, another interpretation of the data is that GCN5 and SPT20 are required for the RLS extension caused by deleting FOB1, possibly because the gcn5∆ mutant already has reduced ERC accumulation (as shown in Figure 3C).
Both should be shown in Figure 3a.
2) The result of experiments without included caspase inhibitor should be shown in Figure 1C.
1- 0,2629/0,3558) = 0,261 has been added to the text In figure 2, some measure of variance should be shown, as error bars, on the plots.
Unfortunately, this is not terribly convincing-the compounds from the initial screen, thioctic acid and parthenolide, are not exactly NF-κB go-to compounds, and the other compounds they test in Figure 4C are barely described and should be shown as a dose-response, not a single, mysterious dose.
3) Given that the water molecules are critical in the wild-type t1A structure, the omit map for the four water molecules should be shown (for Figure 1C or 4A).
In any case, those linear fits, if made, should be shown on the figure.
Data for MO-only injected embryos should be shown (as for Figure 5I), and rescue should be measured against these embryos rather than uninjected controls.
