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A list of the strains used, including those in Supplementary Figures, is reported in Supplementary Table S1.
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28 All figures are reported in Canadian dollars, where $1Cdn was approximately equal to $0.63US at the time of the experiment.
All cost figures are reported in Canadian dollars.
All economic figures are reported in US dollars for the year 2000.
Subset analyses by Child-Pugh stand accompanyingying figures are reported in Supplementary Information.
Similar figures were reported in a study including more than 900 leukoplakia cases in women but not in men (3).
However, much lower figures were reported in Eastern India (16%) [ 16], Cambodia (18%) and Vietnam (25%) [ 29].
Similar mortality figures are reported in Europe, with 1- and 5-year survival rates of only 15% and 4%, respectively [ 2].
A slightly higher percentage was reported by Dhawan et al. (33%) [ 8], yet, lower figures were reported in other studies [ 22].
Of note, the relatively low rates were found in clinical trials (2, 56), whereas the higher figures were reported in retrospective and population-based studies (57– 57).
Pneumococcus was the most lethal germ, with CFR nearly 25%, and similar figures are reported in other regions of the world [ 16, 25, 26].
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