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KRH proposed statistical approaches and computed some of the analyses and provided editorial comments regarding their interpretation and figure presentations.
WWM coordinated the experiments, performed perfusion culture, analyzed specimens in fluorescence microscopy and interpreted results in transmission electron microscopy, designed the figure presentations and wrote the manuscript.
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The figure presentation should start with the current Figure 2, which presents the knockdown strategy and highly convincing evidence for its success at the molecular and cellular level.
The resulting data were compiled into the inverse pole figure presentation of indent microstructures and topographies after Zambaldi and Raabe, Acta Mater.
From the figure presentation, the aluminum and zinc elements are uniformly distributed in the MCP pore surface.
However, the bottom plane of the microwell always resulted in a flat cell contact surface, and confocal images from this plane were used for figure presentation since the actin structures were parallel to and contained within the imaging plane (i.e. parallel to the microwell bottom; Fig. 2C).
Further she made all works dealing with figure presentation.
The right panel is the figure presentation of the pathway.
Each figure presentation was followed by a brief question-and-answer session.
2A) The order of the figure presentation would benefit from reconsideration, especially regarding a more linear presentation.
We thank the reviewers for pointing out the apparent logical gap in the figure presentation that may have generated distraction in Figure 1.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com