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An aggressive tumor cell is able to fight impediments to intravasation posed by the microenvironment such as hypoxia and an immune response using the tools at hand: stromal cells and their secreted factors are hijacked into both helping the tumor cell enter the bloodstream as well as prepare the secondary environment for colonization.
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Atti explained, "The main impediment you fight when you're trying to maintain a 100 gigabyte data rate is heat".
Mr. Bond, handsome and erudite, was the favorite, but Mr. Lewis, with a speaking style that some describe as an impediment, fought hard and brought up Mr. Bond's refusal to take a drug test.
Ignorance due to low levels of education is one of the major impediments to the fight against HIV/Aids in Southern Sudan.
Mayweather had always been cast as the one in the way: the biggest impediment to the fight sports fans wanted to see most.
Founders considering this kind of arrangement should give serious thought to skipping the process and building out a less concentrated revenue base with fewer impediments while your competitors fight to the death.
Even in this age of Barbara Walters, Tom Brokaw and Rudolph Giuliani, why would anyone fight so hard to retain a speech impediment as a sign of singularity?
The fight over domestic security, meanwhile, was another impediment to a bill that, having stalled for months, figured prominently in the election campaign, when Republicans accused Democrats of undercutting it.
"In light of these professionals' key gatekeeper role, in particular in high-risk sectors and activities such as real-estate transactions and the formation of corporations and trusts, this constitutes a serious impediment to Canada's efforts to fight money laundering [or terrorist financing]." Lawyers are able to deposit cash from unknown sources in their trust accounts then disperse these.
Days before the fight, tensions rose after Hopkins mocked Taylor's speech impediment and called him a "phony champion".
Russian government reluctance to providing methadone treatment or clean needles is only one of the fatal impediments to effectively addressing H.I.V. in Russia ("Inadequate Fight Against Drugs Hampers Russia's Ability to Curb H.I.V.," Memo From Russia, Jan . 17.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com