Sentence examples for fidelity of expression from inspiring English sources

The fidelity of expression of the CK19 promoter construct was tested by infection of control B13 cells (negative control) and HepG2 cells.

The ECFP reporter construct was inserted in a large BAC, over 200 kbp in length, to insure fidelity of expression by the normal tissue specific regulatory elements.

This provides evidence of the fidelity of expression and purification of post-translationally modified human type II procollagen from our system.

Our studies demonstrate the fidelity of YFP expression with expression of RUNX2 and other osteogenic genes in hESC-derived osteoprogenitor cells, as well as the osteogenic specificity of YFP signal.

miRNAs are thought to contribute to ensuring the fidelity of gene expression programs in the face of both external stresses and internal transcriptional noise (Li et al. 2009) (reviewed in Hornstein and Shomron 2006; Ebert and Sharp 2012; Posadas and Carthew 2014).

Valencia et al. [ 41] suggested that a functional coupling is usually not essential for gene expression, but enhances the rate and/or efficiency of reactions that may serve to increase fidelity of gene expression in higher eukaryotes.

To ensure a high fidelity of gene expression patterns in embryos a very strict functional requirement exists for the interaction of cis-regulatory modules (CRMs) in the genome of animals during development [1], [2], [3], [4].

These interactions are pivotal for maintaining accurate replication of histone methylation patterns in newly replicated chromatin and in the subsequent fidelity of gene expression.

Nonsense-mediated mRNA decay (NMD) is one of a number of RNA surveillance pathways that help to ensure the fidelity of gene expression by degrading mRNAs that lack the proper arrangement of translational signals (reviewed in [ 1- 4]).

NMD is an eukaryotic mRNA surveillance process that detects, and selectively degrades, mRNA transcripts which harbour premature termination codons (PTC; [ 1]), increasing the fidelity of gene expression by degrading aberrant mRNAs that, if translated, would produce truncated proteins [ 2].

In all organisms, coding sequences differ in codon usage, match to tRNA abundances, mRNA stability and initiation sites to regulate rates and fidelity of protein expression (reviewed in Gingold and Pilpel, 2011).