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On a mechanistic level, disruption of translational fidelity causes protein misfolding and aggregation.
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Emulator-based control can solve the twin problems of stability and fidelity caused by the unwanted transfer system (actuator) dynamics.
Class I retrotransposons move about as a RNA intermediate, which is encoded into DNA before re-entry into the host genome by their endogenous reverse transcriptase enzyme, which is known to be low-fidelity, causing a high mutation rate [ 7, 31].
A contradictory combination of geographical liberty with textual fidelity also causes a stumble in Robert Icke's otherwise superb version of Chekhov's Uncle Vanya at London's Almeida.
The results (Fig. 5B, lower panel) show that mutation in the 5' and 3' flanking sequences reduced translation fidelity and caused significant leakage to the downstream AUG.
That, he said, is, "Fidelity, fidelity, fidelity".
His entry makes him a leading potential challenger to former secretary of State and party heavyweight Hillary Rodham Clinton, if not for votes and campaign donations then for pressing her to maintain fidelity to progressive causes.
Cruz questioned Trump's fidelity to conservative causes, arguing (correctly) that Trump has changed positions and signaled flexibility on his promises to get tough on immigration.
"God's Rottweiler" seized an opportunity during Holy Week to growl, whimper and call upon Roman Catholic dissidents to choose "radical obedience" to the Magisterium over fidelity to such causes as women's ordination, compulsory celibacy for priests and divorce.
Identification of such factors contributes to our comprehension of what causes fidelity to be either high or low, and could help us overcome barriers to adequate implementation in the future.
Their fidelity to the cause of full, fair and understandable financial reporting must be ironclad and unequivocal.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com