Trey Whitfield is not a haven for a gifted few, bound for Horace Mann or Andover on full scholarship and then to the Ivy League.
He put himself in a few binds with errant shots, including two drives on the back nine that landed in hazards, and bonded with Bay Area golf fans, one of whom shouted, "Thanks for coming, Tiger!" as Woods strode down the second fairway.
However, the tagged construct did not fully complement MIG3 deletion, and there were few bound loci not identified in unrelated ChIP experiments (J.A. Lewis and A.P. Gasch, unpublished data).
Clearly, many fewer bound sites are examined by doing this filtering, but the enrichment for likely function is substantial.
Among the CBMs tested, the majority were able to bind to linear, soluble hexose chains (e.g., HEC, lichenan, and PASC, Tables 1, 2), while fewer bound to Avicel and the hemicellulosic substrates, either linear or branched.
Consistent with this idea, reduced levels of cellular Rap1p can cause telomeres to enter recombination pathways at increased frequency (Pardo and Marcand 2005), suggesting that fewer bound Rap1p molecules allow telomeres to behave as DSBs.
Although our data showed that the total number of TFBRs changes little between these closely related species, Caroli/EiJ was found to have overall fewer bound locations, most likely due to differences in the genome qualities.
For example, some proteins use β-ribbon or loop elements for major groove binding, and a few proteins bind into the minor groove.
We further observed that a few yBRDs bind specifically and equally well to certain histone peptides regardless of acetylation, e.g. ySnf2, ySth1 and yBdf2-2 to H3K56 and H3K56ac peptides.
