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This female specific effect was driven by a significant increase in errors in response to happy distracter words (i.e, a positive bias) on placebo [main effect of valence: F 1,14) = 8.3, p =.009] but not following ATD [ F 1,15) = 2.4, p =.14].
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In addition, low levels of royal jelly show similar enhancement for both males and females59, whereas a female-specific effect would be expected if it was acting through an analgous pathway as in honey bees.
The female-specific effect of the HCV transgene raises a question about the relevance of this model to human disease, since it is widely accepted that human HCC is more prevalent in males.
Regarding the influence of Ofil1 and Ofil2, we have found previously [ 11] that they had a female-specific effect on central locomotion in the open field.
We limited the current study to the analysis of young adult females due to the female-specific effect of genotype in our previous studies of young adult Caucasian college students (1).
Given the female-specific effect of the promoter polymorphism on muscle size, we hypothesized that there may be an allele-specific interaction between the estrogen enhancer and the more proximal Sp1 transcription factor site.
Our results show that QTLs on Chr 2T, Chr 3, Chr 4 and Chr 13 have a male-specific effect, and the QTL on Chr 7T has a female-specific effect.
The FSH-lowering allele has previously been found to be associated with male infertility (Grigorova et al., 2008, 2010; Tuttelmann et al., 2012; Simoni and Casarini, 2014), but we found no association with males who had never fathered a child suggesting a female-specific effect, although this may because the phenotype includes males who chose not to have children in addition to infertile males.
It is possible that the splitting of age groups at 0 14 and 15 29 years may have led to a dilution of the number of male cases in the peak age-range which straddle both groups and thus have led to the female-specific effect for deprivation amongst cases of osteosarcoma.
Female-specific effects of GRB14 variants were also detected in previous studies of WHRadjBMI and blood lipids [ 61, 107, 108].
There is little difference in RMSE between the meta-analysis strategies, with all providing equally precise estimates of male- and female-specific effects.
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CEO of Professional Science Editing for Scientists @ prosciediting.com