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That is, these male-to-female transsexuals were different from the control males, shifted towards the female direction on all parameters.
However, although the chromosomal aspect of sex determination is hardwired, the androgens can significantly masculinize the female fetus and antiandrogens can drive the morphological development of the male reproductive system in a female direction.
Thus, both androgens and estrogens are needed to fully differentiate the rodent male brain, while the lack of gonadal hormones is enough to drive the structure in a female direction (see Colciago et al. 2009; McCarthy and Arnold 2011 and Negri-Cesi et al. 2008 for references).
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Thus, from D. melanogaster to D. pseudoobscura, changes in sex-biased states tend to be in the male-to-female direction, whereas the opposite pattern is observed from D. pseudoobscura to D. melanogaster.
Two: a radiocollared he-wolf from Slovenia had crossed the Austrian Alps in mid-winter, entered Italy and was heading in the female's direction.
In particular for females, the direction of wiping after defecation (wiping back to front) can lead to fecal contamination of the urogenital orifices.
Finn's most recent ex-girlfriend Rachel Berry Lea Michelee) is dismayed by his renewed feelings for Quinn, but resolves to concentrate on her career instead of romance, and leads the female New Directions members in a performance of Katy Perry's "Firework".
In homosexual male-to-female transsexuals, the difference does involve sex-dimorphic structures, and the nature of the difference is a shift in the female-typical direction.
Using MRIs of healthy subjects, Witelson et al. (2008) found androphilic men to be shifted towards the female-typical direction relative to gynephilic men.
The most widely discussed neuroanatomic difference between androphilic and gynephilic men was LeVay's (1991) report that the third interstitial nucleus of the anterior hypothalamus (INAH-3) was smaller (i.e., shifted towards the female-typical direction) among androphiles.
Older age, female gender, and direction of the fall again were significantly associated with the likelihood of sustaining an injury.
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