High-fat feeding promoted hepatic lipid accumulation and induced the expression of lipogenic and cholesterogenic genes compared to chow-fed mice: induction of gene expression was found to translate into increased oleate synthesis.
Furthermore, chronic ethanol and/or sucrose feeding promoted significant increase in AST and ALT activities compared to control group.
While we found that cholesterol feeding promoted β-amyloid plaque deposition, it should be noted that this concept is not entirely novel.
Of note, HPD feeding promoted mTORC1 activation and GRP78 upregulation in the cortex of WT mice and inefficient GRP78 upregulation in PGC-1β KO mice (Fig. 6B).
Moreover, cerebellectomy in rodents resulted in reduced food intake when compared with sham-operated animals, which supports a feeding promoting role of the cerebellum in food control [60].
All women in this study had received advice on HIV and infant feeding promoting exclusive breastfeeding in the first six months of the child's life.
Dietary changes including high fat diet (HFD) feeding promotes insulin resistance in rodent models which present useful systems for studying interactions between genetic background and environmental influences contributing to disease susceptibility and progression.
Chronic ethanol feeding promotes a shift of acinar cell apoptosis to necrosis, but little is known about the mechanisms involved.
INSIGHT's central hypothesis is that responsive feeding promotes self-regulation and shared parent child responsibility for feeding, reducing risk for overeating and overweight [ 50].
Ghrelin stimulates appetite, mediates stress-activated feeding, promotes adiposity, and inhibits the effect of CCK on vagal afferent neurons (2, 36– 36).
INSIGHT's central hypothesis is that responsive parenting and specifically responsive feeding promotes self-regulation and shared parent child responsibility for feeding, reducing subsequent risk for overeating and overweight.
