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On the other hand, a pharmacophore is a molecular framework that carries the essential features responsible for a drug's biological response [ 39].
Broadly, there are two relevant main features responsible for maintaining these specifications, PCI signals and Interface.
Molecular features responsible for 5-HT1A andinity and CYP3A4 stability are described.
The key structural features responsible for the inhibition activities were discussed in detail.
This approach selects molecular descriptors that are representative of the molecular features responsible for the relevant molecular activity.
The presence of more number of microporous features, responsible for the quantum confinement effect, leads to an increased PL emission.
This approach requires good molecular descriptors that are representative of the molecular features responsible for the relevant molecular activity.
Investigating the structural features responsible for this difference has a major application in the design of selective anti-schistosomal drugs.
By combining [2] 3D-QSAR, pharmacophore modeling, comparative modeling and molecular docking we could identify features responsible for receptor subtype specificity.
This feature of database may help in identification of the structural features responsible for highly selective or broad-spectrum activity of phytomolecules against different mycobacterial strains.
Employing PCA technique seemed to be a promising way of reducing the informational excess with simultaneous definition of structural features responsible for IL's physicochemical properties.
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