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A transporter-mediated tissue targeting strategy, where the structural features recognized by the transporters are incorporated into the therapeutic molecule, is emerging as an effective approach in drug discovery.
This RNA is double-stranded and carries a 5'-triphosphate moiety, two features recognized by RLRs [18], [19].
We also observed that synaptic tau oligomers shared certain conformational features (recognized by Alz-50 antibody) with larger fibrillar inclusions like NFTs and neuropil threads [ 22, 30, 31].
We defined clinically active disease as the presence of one or more glandular and extraglandular features recognized by the ESSDAI and SSDAI with the exception of fatigue.
These organelle-specific trends have obvious implications for improving the prediction of TMD presence and topology, as TMD features recognized by prediction algorithms will, in part, reflect the localization of the membrane proteins used to train the algorithm.
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More remarkably, our results demonstrate that some molecular mediators, involved in apoptosis induced by pro-oxidant conditions, are deamidated proteins, which can be methylated by PCMT, since they contains the unique feature recognized by this enzyme: the isoaspartyl residue.
The growing plus end is thought to maintain a GTP- or GDP-Pi tubulin cap [8], [9], which would help stabilize the microtubule lattice, and could be the feature recognized by EB1.
Thus, it remains nontrivial to define the precise meaning of "multiple orders of leaf venation," although it is a feature recognized by all botanists.
A user can query chromosomal region of interest, reference SNP ID, HGNC symbols, pathway name or any other unique feature recognized by database as a query.
The localization dependencies depict a hierarchical pathway of recruitment, but the primary chromatin feature recognized by the Mis18 complex is unknown.
Qualitative assessment to be obtained on tissue is (i) the presence or absence of the marker of interest, (ii) the type of cell or feature recognized by the marker, and (iii) the cell morphology (for example, amoeboid, ramified, or dystrophic).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com