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That the effects were found despite this variation in features of sites was encouraging.
We furthermore investigated the sequence features of sites of H3K9me2 nucleation.
Further site-specific features analysis revealed that the features of sites surrounding the central lysine contributed more to the determination of pupylation sites than the other sites.
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Names of algorithms are colored according to whether they consider only sequence or thermodynamic features of site pairing (grey), only site conservation (orange), pairing and contextual features of a site (red), or pairing, contextual features, and site conservation (purple).
Additional features of site context help explain why a given site (e.g., a 7mer-m8 site to miR-1) can be more effective in one 3′ UTR than it is in another.
Hypoxia is a feature of sites of chronic inflammation, for example in the RA synovium, in atherosclerotic plaques, in sites of bacterial infection and at growing tumours [ 48].
Further this change should not alter the coordination chemistry as it retains the essential chemical feature of site 4, a hydroxyl that can contribute to the coordination shell of the permeant ion [31] (Figure 2C).
This disorder feature of site 10 had an index of 72.
There were 2 solvent accessibility features in the top 10 features: the solvent accessibility feature of site 11 had an index of 3, and the solvent accessibility feature of site 21 had an index of 4. In the optimal feature set, there was only 1 disorder feature.
The site combines the social-networking features of Web sites like Facebook with information of interest to its constituency: medical news, career advice, dating resources and travel tips.
The detected high-resolution binding sites can also help analyze sequence features of binding sites where no known motif can be found, and therefore identify possible co-factors.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com