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Rheumatoid arthritis (RA) is one of the inflammatory joint diseases in a heterogeneous group of disorders that share features of destruction of the extracellular matrices of articular cartilage and bone.
When the categorical anatomical phase scoring system in this IP finger joint cohort was used, 10/30 (33.3%) joints were defined as progressors from baseline to 6 months: six of these showing further features of destruction and four of obvious repair in the selected areas of the joint.
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Bone erosion is the only feature of destruction included in the suggested scoring systems for JIA on MRI.
The features of thermooxidative destruction of composites by differential thermogravimetry (DTG /differential thermal analysis (DTA) and the release of BAC from composites into aquatic medium were examined.
A striking feature of SpA is that the joint involvement combines features of bone destruction versus bone remodelling, which distinguishes it from other inflammatory rheumatic disorders, notably rheumatoid arthritis (RA) [ 16].
This system may be suitable to validate or even partially replace complex animal studies and, in particular, address the importance of isolated, specific synovial cell types in an experimental setting which reflects prominent features of joint destruction in RA.
Although features of joint destruction can be dramatic, in particular in some forms of PsA, skeletal damage in SpA is only partially due to the loss of articular cartilage and bone erosion.
"Marvel's The Avengers" features many scenes of destruction in Manhattan, and first responders are present in the film.
Otherwise, cortical thinning of periarticular bone, enhanced by the inflammatory process, is a typical feature of bone destruction in RA [ 3], which can occur as a result of high bone turnover on the inner bone surface.
Including cartilage loss in MRI assessment of RA is important because this feature of joint destruction does not always follow the same pattern of response to therapy as bone erosion does.
Hallmark features of PTOA include destruction of the cartilage matrix in combination with loss of chondrocytes and acute mechanical damage (AMD).
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